MONICA SMITH AT MDACC 9/14/11

MONICA SMITH AT MDACC 9/14/11
MONICA SMITH AT MDACC 9/14/11

Friday, November 5, 2010

Friday: Rituximab Continues and Tumor Lysis

Long night's journey into the day! Joe had a rough night from the effects of the Rituximab,

It is now a little bit after 10AM and Joe's temp is normal, his BP 115/66, HR 86. There is only a little bit of the Rituximab left in the bag. A doctor of the kidneys came in to see Joe since he appears to be having "tumor lysis" which is from the white cells mainly dying from the Rituximab and putting those dead cells give off toxins into his blood stream. They are going watch his blood counts very carefully the rest of today. His potassium level is high so they gave him some meds that will make him poop a bunch. Dr Haigermeister, Lymphoma Doc,  stopped in  to explain the "tumor lysis" some more. The Bad White Blood cells are dying which is a good thing and right now Joe's kidney's are functioning good. The white cells that are dying could clog up his kidneys and if the clog up too much Joe would need dialysis. The need for dialysis has not happened in 15 years since they know how to gets things under control before it happens. The special drug they give Joe is $5000 a dose and he will be given three doses. Oh my! His White Blood count is down to an amazing "7" from  a high of three weeks ago of  "168". WOW!

Bad white blood cells go away and do not come back another day.

It is now 1:22 CST Joe is snoring away. I had left at about 11:00 AM to the studio apartment to walk Max and change clothes. Max is still freaked out from yesterday morning when there was a loud crash behind the stucco wall where he had just taken a poo. When I took him out last night and this morning, he took a pee and wanted to rush right back into the building. Both time, I walked back and forth with him  trying to console him for about 30 minutes but he still would not take a  poo. He shook and he held his tail downward. After Joe checks out, I will take him to the big Dog Park and let him loose and perhaps that will calm him down. Poor dog!

At my request I was handed Joe's last blood test from the draw at 4:30 AM. I will list the main ones below, the normal ranges, the results from Monday, 11/1/10 before the chemo started and the most current ones.
                                                             11/1                         11/5
White Blood Cell Count  (4-11)            56.1                           7.4
Red Blood Count (4.5-6.0)                   3.02                           3.09
Hemoglobin   (14-18)                            8.9                             9.0
Hematocrit    (40-54)                            29.4                          28.9
Platelet Count (140-440)                      76                              26
Neutophil %   (42-66)                           N/A                           83
Lymphocyte % (24-44)                         N/A                           16
Basophil % (0-1)                                   n/a                              1
Neutrophil Absolute Count (1.7-7.3)      N/A                           6.14
Lymphocyte Absolute Count(1-4.8)       n/a                              1.18
Basophil Absolute Count (0-.1)              n/a                              .07

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At 3:15 PM Friday afternoon, Joe's temperature is normal, BP 105/65 HR 73 (Yeah) and oxygen level 97%. Sleeping Man is now awake and alert. He is finally taking a poo which we hope will discard the excess phosphorus serum which was a high 6.5 when the normal ranges are 2.5-4.5. They just took a blood sample to determine where he stands now.

4 comments:

  1. Bonnie:
    Thank you for posting Joe's journey. I wish him the best and you are in my thoughts and prayers daily. I admire your love, determination, and support for your spouse. You are an inspiration.
    Warmly,
    Robin Finkelstein

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  2. Except for the platelets....the counts seem to look better?...that's what I'm getting.

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  3. That is a great response to the chemo. So glad he is feeling better and is less lethargic. That must have been pretty scary for you Bonnie.
    Janet

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  4. Bonnie, this sounds like the normal progression in all areas. Everything sounds like it is going as planned and as expected. I agree with Denise, the platelets, as I had mentioned to you earlier in an email, is something to watch out for, I needed 2 platelet transfusions after part B of the hyperCVAD. And my neutrophils went to zero for almost a week. My white count got as low as 300 (or 0.3 on the scale where 4-10 is normal). The tumorlysis is normal, and just drink lots of water along with the IV flushing I am sure they are doing, I think with sodium bicarbonate. Drinking lots of water with that will help keep the kidneys working. For a while there I think I was up every 2 hours peeing. I was pretty suire his heart rate would come down once his white count went down, and made room for more red cells. Sounds good to me!
    Larry

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